Practical8 min readLast updated: January 2026

Storage and Travel Guide

How to properly store your GLP-1 medication and travel safely with Ozempic, Wegovy, Mounjaro, or Zepbound.

Proper storage is essential to maintain the effectiveness of your GLP-1 medication. This guide covers everything you need to know about storing your medication at home and taking it with you when you travel.

Storage Requirements

Unopened Pens (New)
  • Temperature: Store in refrigerator at 36°F to 46°F (2°C to 8°C)
  • Location: Keep in original carton to protect from light
  • Placement: Store on a shelf, NOT in the freezer compartment
  • Do not freeze: Frozen medication must be discarded
  • Expiration: Check date on packaging—do not use after expiration
Opened/In-Use Pens
  • Options: Can be stored in refrigerator OR at room temperature
  • Room temperature limit: Below 86°F (30°C)
  • Keep away from heat: Don't store near stove, radiator, or in hot car
  • Protect from light: Keep cap on pen when not in use

How Long After Opening?

Ozempic

56 days (8 weeks)

Wegovy

28 days (4 weeks)*

Mounjaro

21 days (3 weeks)

Zepbound

21 days (3 weeks)

*Single-dose pens—use immediately after opening

When to Discard Your Pen

  • If it has been frozen
  • If exposed to temperatures above 86°F (30°C)
  • If the solution is cloudy, discolored, or contains particles
  • If past expiration date or in-use time limit
  • If dropped and the pen may be damaged

Air Travel

Traveling by air with GLP-1 medications requires some planning, but it's straightforward once you know the rules.

TSA Guidelines
  • Medications are exempt from the 3-1-1 liquids rule
  • Injectable medications can go in carry-on luggage
  • Keep in original packaging with pharmacy labels if possible
  • Declare medications to TSA officers at security screening
  • You may bring ice packs, freezer packs, or gel packs to keep medication cool
  • Needles are allowed when accompanied by injectable medication

Packing Tips for Flying

  • ALWAYS carry medication in your carry-on bag: Never put it in checked luggage (cargo holds can freeze)
  • Use an insulated bag: Travel coolers or insulin travel cases work well
  • Include ice packs: Frozen gel packs can keep medication cool for hours
  • Bring extra supplies: Pack extra needles, alcohol swabs, and medication if possible
  • Carry a prescription copy: Helpful for international travel or if questioned
  • Bring a letter from your doctor: Useful for international travel

Pro Tip: Time Zone Changes

If traveling across time zones, take your weekly injection based on the number of days since your last dose, not the local time. Aim for about 7 days between doses—a few hours difference is fine.

Road Trips

Car travel presents unique challenges, especially in extreme temperatures.

Hot Weather

  • Never leave medication in a hot car
  • Use a cooler with ice packs
  • Keep cooler in air-conditioned cabin, not trunk
  • Check temperature periodically if using cooler
  • Don't let medication directly touch ice

Cold Weather

  • Don't leave medication in freezing car
  • Keep medication close to your body in cold weather
  • Bring inside with you at rest stops
  • Use an insulated pouch if walking in cold

Hotel and Vacation Storage

At Your Hotel

  • Request a mini-fridge: Most hotels provide one upon request (often free for medical needs)
  • Check the temperature: Hotel fridges can sometimes freeze items—test with water first
  • Don't use the freezer: Store only in the refrigerator section
  • Alternative: Your pen can stay at room temperature (under 86°F) during your trip if refrigeration isn't available

Cruises

  • Contact the cruise line in advance about medication storage
  • Request a cabin with a refrigerator or mini-bar you can use
  • Some ships' medical centers can store medications
  • Bring enough supplies for the entire trip plus extras

Camping/Outdoors

  • Use a high-quality insulated cooler with ice packs
  • Keep medication wrapped to prevent direct contact with ice
  • Refresh ice packs as needed
  • Consider the pen can be at room temperature for up to 3 weeks (if under 86°F)
  • Time your injection for before the trip if possible

Travel Checklist

What to Pack

Medication pen(s)
Extra pen needles
Alcohol swabs
Sharps container
Insulated travel case
Ice/gel packs
Prescription copy
Doctor's letter (international)

International Travel Tips

  • Carry a doctor's letter: Include your diagnosis, medication name, and necessity for treatment
  • Know the brand names: Your medication may have different names in other countries
  • Research your destination: Some countries have restrictions on injectable medications
  • Bring enough medication: Plus extra in case of delays
  • Know your embassy contact: In case you need emergency medication replacement
  • Travel insurance: Ensure it covers medication replacement if needed

Emergency Situations

If Your Medication Was Exposed to Extreme Temperatures
  • Don't use it: When in doubt, throw it out
  • Contact your pharmacy: They may be able to provide an emergency supply
  • Call your doctor: They can send a new prescription
  • Document the incident: For insurance purposes
  • Check manufacturer programs: Some offer replacement for damaged medication

With proper planning, you can travel confidently with your GLP-1 medication. The key is keeping it within the right temperature range and always having it accessible in your carry-on when flying.

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Medical Disclaimer: This guide is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting any medication.

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