ComparisonAugust 24, 202611 min read

GLP-1 Provider Comparison: Side by Side

A direct comparison of leading GLP-1 providers across the criteria that actually differ: pricing structure, pharmacy disclosure, lab requirements and cancellation terms.

Sema VS Tirz Team

Provider websites all say roughly the same things. What separates them shows up only when you line up the specifics: whether the price holds as you titrate, whether they name a pharmacy, whether labs are included, and whether you can actually leave. This page puts those side by side.

Pricing Structure

ProviderPricing ModelEntry Price
CoreAge Rx Plan-length tiersFrom $99/mo on 12 months
Precision Telemed Flat across all doses$199 first month, then $249.99/mo
NexLife Flat across doses, tiered by plan length$119 to $139/mo semaglutide
VITAstir Tiered by dose strength$145 at 2.5 mg, up to $599 at 15 mg
Fifty 410 Two dose tiers$133/mo tirzepatide starter
Gimme Care All-inclusive, 1 or 3 months$130 to $160/mo semaglutide
Shapely Membership plus medication$99/mo medication plus $49 to $99 membership
Klinic Per visit plus medication$99 initial visit, $75 follow-up
Midi Health Per visit plus medication$250 initial self-pay, or insurance

Pharmacy Disclosure

ProviderPharmacy Named?Type
Precision Telemed Yes, Rush Pharmacy503A compounding pharmacy
Freedom Weight Loss Clinic Yes, MedRx Pharmacy, HoustonNot specified
NexLife Yes, five partners namedBoth 503A and 503B referenced
VITAstir No, but PCAB-accreditedPCAB-accredited sterile pharmacy
Healthon No, but batch testedNetwork pharmacies, independently tested
Fifty 410 NoIndependent FDA-registered 503A
LifeRx.md No503A pharmacies
Belle NoNot specified
LillyDirect Manufacturer's own pharmacyNo compounding involved
NovoCare Pharmacy Manufacturer's own pharmacyNo compounding involved

Labs and Clinical Involvement

ProviderLabsClinical Model
Fridays Included through Quest, no lab feesUnlimited clinician visits
Shapely Recommended, $75 self-pay at LabcorpMonthly video visits plus dietitians
Midi Health Targeted labs as part of the care plan30-min initial, 15-min follow-ups
Medi-Weightloss Included at the new patient visitWeekly in-person visits
LifeRx.md Coordinated as part of the care planState-licensed provider review
Precision Telemed Not publishedPhysician review, often same day
Gimme Care Not publishedLicensed US provider review
Belle Not published5-minute intake, clinician review

Coverage and Payment

ProviderStatesInsurance / HSA-FSA
Gimme Care All 50 plus DCSelf-pay; HSA/FSA not published
Precision Telemed All 50Self-pay; HSA and FSA accepted
LifeRx.md All 50No insurance required
Klinic All 50Major insurers, Medicare Part D, Medicaid
Midi Health All 50In-network with major carriers
Alloy All 50 plus DCFSA and HSA cards accepted
Freedom Weight Loss Clinic 31 states plus DCHSA, FSA and flex only
Shapely CA, FL, NY, TX onlyMedicare and major PPOs
Medi-Weightloss 140+ clinic locationsMany locations accept insurance; HSA/FSA

Cancellation Terms

No subscription at all

Fifty 410 , Freedom Weight Loss Clinic , Direct Meds and VITAstir and SkinnyVIP sell per order rather than by subscription, so there is nothing to cancel. SkinnyVIP also refunds in full if a clinician does not prescribe.

Cancel any time, published

Precision Telemed , WellMedr and Fridays publish cancel-any-time terms, though Fridays' refund policy is narrow and most fees are non-refundable.

Not published

Belle , Gimme Care , Alloy , Shapely and Klinic do not publish cancellation terms. Ask in writing before enrolling.

Prepaid plans

NexLife , Fridays , Cora Health , Ondra Health and REMEVi reach their lowest rates through prepaid multi-month plans, and their refund terms differ sharply: Cora pro-rates, Ondra treats all charges as final once a prescription is transmitted. Our refund and cancellation comparison sets out each.

Brand-Name Versus Compounded at a Glance

CategoryProvidersTypical Cost
Compounded onlyCoreAge Rx, Precision Telemed, NexLife, Gimme Care, Fifty 410, Belle, VITAstir, Healthon, WellMedr, Direct Meds$99 to $250/mo
Brand-name only LillyDirect , NovoCare Pharmacy , Klinic , Heally $149 to $699/mo self-pay
Both Fridays , Midi Health , Shapely , Zealthy , Medi-Weightloss Varies by route chosen

See our [brand-name versus compounded guide](/articles/brand-name-vs-compounded-glp1) for how to choose between them.

Picking Based on What You Care About

Frequently Asked Questions

Which GLP-1 provider is best overall?

It depends what you weight. Our best online GLP-1 providers ranking puts CoreAge Rx first on overall value, but a patient prioritising insurance coverage would be better served by Klinic or Midi Health, and one prioritising FDA-approved medication by LillyDirect or NovoCare Pharmacy.

Which providers charge the same at every dose?

Precision Telemed publishes a flat $249.99 a month across the full 2 mg to 15 mg tirzepatide range, and NexLife states its price is the same at every dose. Most other compounded providers tier by dose, sometimes steeply.

Which providers name their pharmacy?

Precision Telemed names Rush Pharmacy, Freedom Weight Loss Clinic names MedRx Pharmacy in Houston, and NexLife names five partners spanning 503A and 503B facilities. Most compounded providers do not name theirs.

Which providers take insurance?

Klinic accepts major insurers including Medicare Part D and Medicaid. Midi Health is in-network with Blue Cross, UnitedHealthcare, Cigna and Aetna. Shapely accepts Medicare and major PPOs. Zealthy pursues brand-name coverage. Compounded medication is generally not covered anywhere.

Which providers cover all 50 states?

Gimme Care publishes all 50 states plus DC, as does Alloy. Precision Telemed, LifeRx.md, Klinic and Midi Health all publish all 50 states. Shapely serves only California, Florida, New York and Texas, and Freedom Weight Loss Clinic serves 31 states plus DC.

What should I compare that providers do not advertise?

The price at your maintenance dose rather than your starting dose, the pharmacy name and its 503A or 503B status, whether labs are included, whether membership is charged separately from medication, and what happens to prepaid months if you cancel early.

Medical Disclaimer

This article is general information, not medical advice. GLP-1 medications are prescription drugs with real risks and contraindications, and only a licensed clinician who knows your history can decide whether one is appropriate for you. Prices, programs and policies described here reflect what providers published at the time of writing and change frequently; verify everything directly before enrolling. Read our full medical disclaimer.

Last reviewed: August 24, 2026

#1 Recommended

Ready to Get Started?

CoreAge Rx is our top-rated provider for compounded Semaglutide and Tirzepatide. They offer legitimate, 503B pharmacy-sourced medications at a fraction of brand-name prices.

  • Compounded Semaglutide from $99/mo (12-month plan)
  • Compounded Tirzepatide from $299/month
  • US-licensed physicians and 503B pharmacies
  • Free shipping, no hidden fees

Medical Disclaimer: This article is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

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